AMH, anti-Mullerian hormone, 268

N. diseases: 242; N. variants: 12
Disease: Nephroblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.030 AlteredExpression disease BEFREE The WT1 is an essential factor for activation of the Mis promoter; therefore, the persistence of the mullerian duct in patients with Denys-Drash syndrome may result from deregulation of the MIS gene. 12855602 2003
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.030 Biomarker disease BEFREE Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome gene 1 (DAX-1) inhibits SF-1-mediated induction of MIS and other steroidogenic genes, whereas Wilms' tumor suppressor gene (WT1) augments SF-1-mediated MIS expression. 12213901 2002
CUI: C0027708
Disease: Nephroblastoma
Nephroblastoma 		0.030 AlteredExpression disease BEFREE Here, we show that WT1 -KTS isoforms associate and synergize with SF-1 to promote MIS expression. 9590178 1998