GIP, gastric inhibitory polypeptide, 2695

N. diseases: 110; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE Herein, we examine whether the chronic treatment with the novel dual GLP-1/GIP receptor agonist DA-CH3 can restore the cognitive decline and AD-like cerebral pathology of the APPSWE/PS1ΔE9 mouse model at the age of 10 months old. 30282365 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE A novel GLP-1/GIP/Gcg triagonist reduces cognitive deficits and pathology in the 3xTg mouse model of Alzheimer's disease. 29473979 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition
0.030 Biomarker disease BEFREE A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model. 28342971 2017