GJA8, gap junction protein alpha 8, 2703

N. diseases: 82; N. variants: 21
Disease: Age-related cataract ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.040 Biomarker disease BEFREE The impact of GJA8 SNPs on susceptibility to age-related cataract. 30349978 2018
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.040 GeneticVariation disease BEFREE Both Cx46 and Cx50 are crucial for lens transparency; mutations in their genes have been linked to congenital and age-related cataracts. 28124626 2017
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.040 GeneticVariation disease BEFREE The genetic mutation in GJA3, GJA8, and LIM2 may slightly contribute to the development of age-related cataracts. 21386927 2011
CUI: C0036646
Disease: Age-related cataract
Age-related cataract 		0.040 Biomarker disease BEFREE These results support that the GJA8 gene may be a novel susceptibility gene for age-related cataracts. 20582632 2011