SNX5, sorting nexin 5, 27131

N. diseases: 24; N. variants: 3
Disease: Malignant neoplasm of thyroid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007115
Disease: Malignant neoplasm of thyroid
Malignant neoplasm of thyroid 		0.010 Biomarker disease BEFREE Furthermore, a thyroid cancer model using carcinogen and an anti-thyroidal agent revealed that Snx5<sup>-/-</sup> mice developed metastasizing thyroid tumors with activation of MAP kinase and AKT pathways, which are postulated to be major pathways of malignant progression of human thyroid carcinoma. 28771744 2017