AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.030 GeneticVariation disease BEFREE We genotyped AGO1 rs636832A/G, AGO2 rs7005286C/T, AGO2 rs11166985A/G and AGO2 rs2292779C/G polymorphisms in 184 Graves' disease (GD) patients, 195 Hashimoto's disease (HD) patients and 122 healthy volunteers using the polymerase chain reaction-restriction fragment length polymorphism method. 29256262 2018
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.030 Biomarker disease BEFREE Argonaute 2 immunoprecipitation revealed 1142 genes consistently targeted by miRNAs in at least three of four HL cell lines. 28432871 2017
CUI: C0019829
Disease: Hodgkin Disease
Hodgkin Disease
0.030 Biomarker disease BEFREE To identify the miR-155 targets relevant for B-cell lymphoma, we performed RNA immunoprecipitation of Argonaute 2 in Hodgkin lymphoma (HL) cells upon miR-155 inhibition and in BL cells upon ectopic expression of miR-155. 26497687 2016