AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE We also identified decreased overall AGO expression in melanoma derived cell lines compared to other tumor cell lines and normal tissues, with the largest differences in AGO2 expression. 27518285 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE We could show that re-expression of AGO2 in melanoma leads to a strong improvement of regulatory effects due to increased functionality of small-interfering RNAs and short hairpin RNAs. 24169347 2013