AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 Biomarker disease BEFREE These results support the notion that the cereblon binding partner AGO2 plays an important role in regulating MM cell growth and survival and AGO2 could be considered as a novel drug target for overcoming IMiD resistance in MM cells. 27142104 2016
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 Biomarker disease BEFREE Moreover, a chick chorioallantoic membrane (CAM) assay was used to demonstrate that AGO2 could drive neovessel formation in MM lines in vivo. 24886719 2014
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.030 AlteredExpression disease BEFREE High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2. 20385818 2010