AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Disease: Paratuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030524
Disease: Paratuberculosis
Paratuberculosis 		0.010 Biomarker disease BEFREE PD-L1 blockade induced J-PPD-stimulated CD8<sup>+</sup> T-cell proliferation and interferon gamma production <i>in vitro</i> Combined treatment with a COX-2 inhibitor and anti-PD-L1 antibodies enhanced J-PPD-stimulated CD8<sup>+</sup> T-cell proliferation <i>in vitro</i>, suggesting that the blockade of both pathways is a potential therapeutic strategy to control Johne's disease. 29483289 2018