AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 Biomarker phenotype BEFREE Taken together, these results indicate that oncogenic circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes. 30341421 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 Biomarker phenotype BEFREE Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis. 30305728 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.030 AlteredExpression phenotype BEFREE In conclusion, Drosha, Dicer, Argonaute 1, and Argonaute 2 are differentially expressed at different metastatic sites in ovarian carcinoma compared with primary carcinomas, suggesting a role for these molecules in tumor progression. 22647351 2012