AGO2, argonaute RISC catalytic component 2, 27161

N. diseases: 186; N. variants: 11
Disease: Carcinoma of bladder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder 		0.030 Biomarker disease BEFREE Despite ongoing research on bladder biomarkers, the clinicopathological impact and diagnostic function of miRNA maturation regulators Drosha and Argonaute proteins AGO1 and AGO2 in urothelial bladder carcinoma remain unclear. 29857476 2018
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder 		0.030 AlteredExpression disease BEFREE In conclusion, EIF2C2, Dicer, and Drosha are more highly expressed in bladder carcinoma, promote the development of bladder cancer, and suggested a poor prognosis. 25656609 2015
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder 		0.030 Biomarker disease BEFREE Secreted miRNA characterized from isogenic bladder carcinoma cell lines with differing metastatic potential were uncoupled from binding to target transcripts or the AGO2-miRISC complex. 25261234 2014