GLA, galactosidase alpha, 2717

N. diseases: 190; N. variants: 203
Disease: Cardiac Arrhythmia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia 		0.120 GeneticVariation phenotype BEFREE Anderson-Fabry disease (FD), an X-linked recessive lysosomal storage disorder caused by a deficiency of α-galactosidase A (α-Gal A) activity, is associated with cardiac manifestations including arrhythmias, valvular abnormalities, and cardiomyopathy. 22378313 2012
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia 		0.120 GeneticVariation phenotype BEFREE Fabry disease is an X-linked lysosomal storage disorder caused by mutations of the α-galactosidase A (GLA) gene, and the disease is a relatively prevalent cause of left ventricular hypertrophy followed by conduction abnormalities and arrhythmias. 21333496 2011
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia 		0.120 Biomarker phenotype HPO