Malignant neoplasm of prostate
|
0.370 |
Biomarker
|
disease |
BEFREE |
This inverse relationship between miR-182 and ZIP1 also occurs in human prostate cancer tissue, which is known for Zn loss.
|
30397150 |
2018 |
Malignant neoplasm of prostate
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
RREB-1 overexpression results in down-regulation of hZIP1 and contributes to the loss of hZIP1 expression and zinc in prostate cancer.
|
21360563 |
2011 |
Malignant neoplasm of prostate
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Recent studies reveal a strong association between prostate cancer progression and the downregulation of the zinc uptake transporters hZip1 and hZip3.
|
21940908 |
2011 |
Malignant neoplasm of prostate
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
The Ras pathway and activation of RREB-1 are involved in hZIP1 down-regulation and may play a role in the decrease of the transporter expression in prostate cancer.
|
19802870 |
2010 |
Malignant neoplasm of prostate
|
0.370 |
Biomarker
|
disease |
CTD_human |
Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study.
|
19208208 |
2009 |
Malignant neoplasm of prostate
|
0.370 |
Biomarker
|
disease |
BEFREE |
Our results show that hZIP1 overexpression has a functional effect on the malignant potential of prostate cancer cells via inhibition of NF-kappaB-dependent pathways and support the concept that hZIP1 may function as a tumor suppressor gene in prostate cancer.
|
18765529 |
2008 |
Malignant neoplasm of prostate
|
0.370 |
Biomarker
|
disease |
CTD_human |
The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots.
|
16700911 |
2006 |
Malignant neoplasm of prostate
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
To address this issue, the expression of hZIP1 and the depletion of zinc in malignant versus non-malignant prostate glands of prostate cancer tissue sections were analyzed. hZIP1 expression was also determined in malignant prostate cell lines.
|
16153295 |
2005 |
Malignant neoplasm of prostate
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
We have evaluated 58 prostate cancer tissues in 2 major racial groups (30 from whites and 28 from African Americans) for their ability to express 2 major human zinc transporters, hZIP1 and hZIP2.
|
12966353 |
2003 |
Prostatic Neoplasms
|
0.330 |
Biomarker
|
group |
CTD_human |
Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study.
|
19208208 |
2009 |
Prostatic Neoplasms
|
0.330 |
AlteredExpression
|
group |
LHGDN |
Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells.
|
19026724 |
2009 |
Prostatic Neoplasms
|
0.330 |
AlteredExpression
|
group |
LHGDN |
The effect of hZIP1 overexpression on prostate tumor progression in vivo was assessed using a xenograft model.
|
18765529 |
2008 |
Prostatic Neoplasms
|
0.330 |
AlteredExpression
|
group |
BEFREE |
The effect of hZIP1 overexpression on prostate tumor progression in vivo was assessed using a xenograft model.
|
18765529 |
2008 |
Prostatic Neoplasms
|
0.330 |
Biomarker
|
group |
CTD_human |
The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots.
|
16700911 |
2006 |
Prostatic Neoplasms
|
0.330 |
Biomarker
|
group |
LHGDN |
hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer.
|
16153295 |
2005 |
Respiratory Hypersensitivity
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation.
|
17085522 |
2007 |
Prostate carcinoma
|
0.070 |
Biomarker
|
disease |
BEFREE |
This inverse relationship between miR-182 and ZIP1 also occurs in human prostate cancer tissue, which is known for Zn loss.
|
30397150 |
2018 |
Prostate carcinoma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
Recent studies reveal a strong association between prostate cancer progression and the downregulation of the zinc uptake transporters hZip1 and hZip3.
|
21940908 |
2011 |
Prostate carcinoma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
RREB-1 overexpression results in down-regulation of hZIP1 and contributes to the loss of hZIP1 expression and zinc in prostate cancer.
|
21360563 |
2011 |
Prostate carcinoma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
The Ras pathway and activation of RREB-1 are involved in hZIP1 down-regulation and may play a role in the decrease of the transporter expression in prostate cancer.
|
19802870 |
2010 |
Prostate carcinoma
|
0.070 |
Biomarker
|
disease |
BEFREE |
Our results show that hZIP1 overexpression has a functional effect on the malignant potential of prostate cancer cells via inhibition of NF-kappaB-dependent pathways and support the concept that hZIP1 may function as a tumor suppressor gene in prostate cancer.
|
18765529 |
2008 |
Prostate carcinoma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
To address this issue, the expression of hZIP1 and the depletion of zinc in malignant versus non-malignant prostate glands of prostate cancer tissue sections were analyzed. hZIP1 expression was also determined in malignant prostate cell lines.
|
16153295 |
2005 |
Prostate carcinoma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
We have evaluated 58 prostate cancer tissues in 2 major racial groups (30 from whites and 28 from African Americans) for their ability to express 2 major human zinc transporters, hZIP1 and hZIP2.
|
12966353 |
2003 |
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
SLC39A1 is a Zn(2+) transporter and its role in tumour suppression has been shown in prostate.
|
27118869 |
2016 |
Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Results suggest that hZIP1 may act as a tumor suppressor in ccRCC. hZIP1 is closely correlated with clinicopathological features.
|
24878177 |
2014 |