Autistic Disorder
|
0.380 |
Biomarker
|
disease |
BEFREE |
Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear.
|
22291444 |
2012 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
BEFREE |
Disrupted in schizophrenia 1 (DISC1) is a leading candidate susceptibility gene for schizophrenia, bipolar disorder and recurrent major depression, which has been implicated in other psychiatric illnesses of neurodevelopmental origin, including autism.
|
22434823 |
2012 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
BEFREE |
Disrupted in schizophrenia 1 (DISC1) is one of the strongest supported risk genes for psychiatric disorders, such as schizophrenia, major depression, bipolar disorder, and autism.
|
21757008 |
2011 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
LHGDN |
We established association between autism and a DISC1 intragenic microsatellite (D1S2709; P=0.004).
|
17579608 |
2008 |
Autistic Disorder
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
DISC1 duplication in two brothers with autism and mild mental retardation.
|
20002455 |
2010 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
BEFREE |
We established association between autism and a DISC1 intragenic microsatellite (D1S2709; P=0.004).
|
17579608 |
2008 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
BEFREE |
Disrupted-in-schizophrenia-1 (DISC1) is one of major susceptibility factors for a wide range of mental illnesses, including schizophrenia, bipolar disorder, major depression and autism spectrum conditions.
|
18762802 |
2008 |
Autistic Disorder
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
Disrupted in schizophrenia 1 (DISC1) has been associated with risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression, autism and Asperger syndrome, but apart from in the original translocation family, true causal variants have yet to be confirmed.
|
18317464 |
2009 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
CTD_human |
We established association between autism and a DISC1 intragenic microsatellite (D1S2709; P=0.004).
|
17579608 |
2008 |
Autistic Disorder
|
0.380 |
Biomarker
|
disease |
CTD_human |
The duplication contains seven genes including the DISC1 gene, an interesting candidate gene that has been associated to schizophrenia, bipolar disorder, autism and Asperger syndrome.
|
20002455 |
2010 |
Autistic Disorder
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
We genotyped seven tag single nucleotide polymorphisms (SNPs) in DISC1, spanning 338 kb, in 367 autism trios (singleton and their biological parents) including 1,101 individuals.
|
21569632 |
2011 |