DISC1, DISC1 scaffold protein, 27185

N. diseases: 136; N. variants: 44
Disease: Lissencephaly ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0266463
Disease: Lissencephaly
Lissencephaly 		0.020 GeneticVariation disease BEFREE Whereas severe presentations of "lissencephaly" are associated with mutations and deletions of DISC1, LIS1 and the gene for the very low-density lipoprotein receptor, genetic variations of these loci are good candidate schizophrenia genes. 20207112 2010
CUI: C0266463
Disease: Lissencephaly
Lissencephaly 		0.020 Biomarker disease BEFREE NudE-Like (NDEL1/NUDEL), through its interaction with LIS1 and DISC1, has been implicated in the etiology of neurological disorders such as lissencephaly and schizophrenia, respectively. 17482883 2007