DISC1, DISC1 scaffold protein, 27185

N. diseases: 136; N. variants: 44
Disease: Schizophrenia and related disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0809983
Disease: Schizophrenia and related disorders
Schizophrenia and related disorders 		0.030 Biomarker group BEFREE In the developing field of biological psychiatry, DISC1 stands out by virtue of there being credible evidence, both genetic and biological, for a role in determining susceptibility to schizophrenia and related disorders. 16843095 2006
CUI: C0809983
Disease: Schizophrenia and related disorders
Schizophrenia and related disorders 		0.030 Biomarker group BEFREE Thus, both genetic and functional data provide evidence for a critical role for DISC1 in schizophrenia and related disorders, supporting the neurodevelopmental hypothesis for the molecular pathogenesis of these devastating illnesses. 16699061 2006
CUI: C0809983
Disease: Schizophrenia and related disorders
Schizophrenia and related disorders 		0.030 GeneticVariation group BEFREE These findings are consistent with the possibility that mutations in the DISC1 gene can increase the risk for schizophrenia and related disorders. 15940305 2005