GNMT, glycine N-methyltransferase, 27232

N. diseases: 57; N. variants: 5
Disease: Fatty Liver Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.020 AlteredExpression disease BEFREE Instead, liver GNMT mRNA expression was decreased in those with NASH (P = 3.8 x 10<sup>-4</sup> ) and correlated with liver PC content (r<sub>s</sub>  = 0.265, P = 0.001). 31199045 2019
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease 		0.020 AlteredExpression disease BEFREE In NAFLD, GNMT expression is controlled by miR-873-5p in the hepatocytes, leading to disruptions in mitochondrial functionality in a preclinical murine non-alcoholic steatohepatitis (NASH) model. 31668391 2019