ERLEC1, endoplasmic reticulum lectin 1, 27248

N. diseases: 17; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease 		0.300 Biomarker phenotype CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Biomarker disease CTD_human Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. 26881866 2016
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. 31308545 2019
CUI: C0376154
Disease: Skin callus
Skin callus 		0.020 Biomarker disease BEFREE In contrast, exogenous JA treatment during callus formation on CIM did not influence the plant regeneration process. 31094274 2019
CUI: C0376154
Disease: Skin callus
Skin callus 		0.020 Biomarker disease BEFREE The 74-88% callus induction frequency was obtained on CIM-1 to CIM-5. 31218181 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker group BEFREE Tumours were selected with the following phenotypical features, using mucin histochemical and immunohistochemical analyses, in addition to their morphological features: (1) tumours with an extremely well-preserved gastric foveolar phenotype (foveolar-type); (2) tumours with an extremely well-preserved complete-type intestinal metaplastic phenotype (CIM-type); and (3) ordinary tumours without extreme phenotypes (ordinary-type). 10878546 2000
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker group BEFREE The incidence of MSI-H was found to be significantly higher in foveolar-type tumors (100%; 4 of 4) than in ordinary-type (19%; 10 of 52) or CIM-type tumors (0%; 0 of 5) (P < .01). 11014567 2000
CUI: C0039144
Disease: Syringomyelia
Syringomyelia 		0.010 Biomarker disease BEFREE Scoliotic patients with CIM were generally offered surgery only when there was a large syrinx. 29532166 2018
CUI: C0039147
Disease: Syrinx formation
Syrinx formation 		0.010 Biomarker disease BEFREE Scoliotic patients with CIM were generally offered surgery only when there was a large syrinx. 29532166 2018
CUI: C1306587
Disease: Acute encephalopathy
Acute encephalopathy 		0.010 GeneticVariation disease BEFREE Our results revealed that having at least one CIM allele is a risk factor for the onset of acute encephalopathy, regardless of its antecedent infections. 20934285 2011
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.010 Biomarker phenotype BEFREE In this study, we report the identification of a novel cancer invasion and metastasis-related gene (hereafter referred to as CIM, also called ERLEC1), which influences both of these stress-response pathways to promote metastasis. 21118962 2010
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.010 AlteredExpression disease BEFREE Ectopic expression of CIM in lung cancer cells increased their tolerance to hypoxia. 21118962 2010
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.010 AlteredExpression disease BEFREE Ectopic expression of CIM in lung cancer cells increased their tolerance to hypoxia. 21118962 2010
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.010 AlteredExpression disease BEFREE Ectopic expression of CIM in lung cancer cells increased their tolerance to hypoxia. 21118962 2010