Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker disease BEFREE Herein, we investigated the cytotoxicity of GNPs toward lung cancer cells under the glutamate cysteine ligase catalytic subunit (GCLC) was silenced by siRNA. 25789740 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker disease BEFREE This study investigated the expression of Nrf2 and of Nrf2-targeted genes (NQO1 and GCLC) and the genes for the metallothionein (MT) isoforms (MT-1A and MT-2A) in human lung cancer and cancer-surrounding tissues. 23947958 2013
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 AlteredExpression disease BEFREE Carboplatin AUC and gamma-glutamylcysteine synthetase gene expression in peripheral mononuclear cells of lung cancer patients. 11911273 2002
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 AlteredExpression disease BEFREE Proximal 5'-flanking sequence of the human gamma-glutamylcysteine synthetase heavy subunit gene is involved in cisplatin-induced transcriptional up-regulation in a lung cancer cell line SBC-3. 9245699 1997