|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
RNA-Binding Protein HuR Regulates Both Mutant and Wild-Type IDH1 in IDH1-Mutated Cancer.
|
30266754 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
RNA‑binding protein‑mediated post‑transcriptional regulation is important in the initiation and development of cancer.
|
29658587 |
2018 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Finally, luciferase reporter assays and RNA-binding protein immunoprecipitation assays suggest that this is due to MEX3B binding to the 3' untranslated region (UTR) of <i>HLA-A</i> to destabilize the mRNA.<b>Conclusions:</b> MEX3B mediates resistance to cancer immunotherapy by binding to the 3' UTR of <i>HLA-A</i> to destabilize the <i>HLA-A</i> mRNA and thus downregulate HLA-A expression on the surface of tumor cells, thereby making the tumor cells unable to be recognized and killed by T cells.<i>Clin Cancer Res; 24(14); 3366-76.
|
29496759 |
2018 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The role of RNA-binding protein tristetraprolin in cancer and immunity.
|
29124478 |
2017 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer.
|
27940961 |
2016 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The RNA-binding protein LARP4 regulates cancer cell migration and invasion.
|
27615744 |
2016 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
LIN28 is an evolutionarily conserved RNA-binding protein with critical functions in developmental timing and cancer.
|
26149387 |
2015 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Integrative genomic analyses of the RNA-binding protein, RNPC1, and its potential role in cancer prediction.
|
26046131 |
2015 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.
|
24722255 |
2014 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Musashi RNA-binding protein1 (Msi1), a member of the RNA-binding protein family, has been reported to be a diagnostic marker and potential therapeutic target in some cancers, its function in cervical cancer remains unknown.
|
25362645 |
2014 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
HuR, an RNA-binding protein, acts under acute stress to regulate core signaling pathways in cancer through post-transcriptional regulation of mRNA targets.
|
23807417 |
2013 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The function of the RNA-binding protein hnRNP in cancer metastasis.
|
24516048 |
2013 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The RNA-binding protein Sam68 is a multifunctional player in human cancer.
|
21565971 |
2011 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The RNA-binding protein HuR is highly abundant in many cancers.
|
20305372 |
2010 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The RNA-binding protein tristetraprolin (TTP) regulates expression of many cancer-associated and proinflammatory factors through binding AU-rich elements (ARE) in the 3'-untranslated region (3'UTR) and facilitating rapid mRNA decay.
|
20157568 |
2009 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Regulation of gene expression by the RNA-binding protein Sam68 in cancer.
|
18481990 |
2008 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Targeting the RNA-binding protein Sam68 as a treatment for cancer?
|
17927519 |
2007 |
|
Malignant Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Immunohistochemical analysis of paired tumor and normal tissue specimens revealed that the expression and cytoplasmic abundance of the RNA-binding protein HuR increased with malignancy, particularly in colon carcinomas.
|
14562043 |
2003 |