GLI3, GLI family zinc finger 3, 2737

N. diseases: 400; N. variants: 73
Disease: Hydronephrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.130 AlteredExpression disease BEFREE Constitutive expression of GLI3 repressor in <i>Ptch1-</i>deficient mice rescued ectopic <i>Ptch2</i> expression and obstructive hydronephrosis. 29109083 2018
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.130 AlteredExpression disease BEFREE On the other hand, Gli3 repressor activity was enhanced, possibly contributing to hydronephrosis and impaired glomerulogenesis in some animals. 28615245 2017
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.130 Biomarker disease BEFREE Here, we review the pathobiology and clinical management of non-obstructive hydronephrosis and describe how inhibitors of GLI3 repressor formation may serve as novel therapies for this disorder. 23052658 2013
CUI: C0020295
Disease: Hydronephrosis
Hydronephrosis 		0.130 Biomarker disease HPO