GLO1, glyoxalase I, 2739

N. diseases: 137; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1263666
Disease: Advanced cirrhosis
Advanced cirrhosis
0.020 AlteredExpression disease BEFREE In primary hepatocytes, hepatic stellate cells (pHSC) and sinusoidal endothelial cells (pLSEC) from rats with early (CCl4 8wk) and advanced cirrhosis (CCl4 12wk) expression and activity of Glo-I were determined and compared to control. 28231326 2017
CUI: C1263666
Disease: Advanced cirrhosis
Advanced cirrhosis
0.020 AlteredExpression disease BEFREE Glo-I expression was found to be reduced in early and advanced cirrhosis with a subsequent increase of MGO-levels. 29156655 2017