HTRA2, HtrA serine peptidase 2, 27429

N. diseases: 151; N. variants: 6
Disease: Parkinsonian Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242422
Disease: Parkinsonian Disorders
Parkinsonian Disorders 		0.320 GeneticVariation group BEFREE Twenty-nine of 109 probands with autosomal-recessive inheritance of parkinsonism (26.6%) were found to carry mutations in Parkin, PINK1, GBA, or HTRA2. 30788857 2019
CUI: C0242422
Disease: Parkinsonian Disorders
Parkinsonian Disorders 		0.320 Biomarker group BEFREE HTRA2 and PINK1 loss of function causes parkinsonism in humans and animals. 29050400 2017
CUI: C0242422
Disease: Parkinsonian Disorders
Parkinsonian Disorders 		0.320 Biomarker group CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015