EML4, EMAP like 4, 27436

N. diseases: 10; N. variants: 2
Disease: Neoplasm Metastasis ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.330 Biomarker phenotype CTD_human We report the case of an adenocarcinoma of the lung associated with metachronous miliary brain and lung metastases with an echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) gene translocation. 22999080 2012
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.330 Biomarker phenotype CTD_human We present the clinicopathologic features of three patients with metastatic NSCLC harboring the EML4-ALK translocation that developed isolated central nervous system (CNS) metastases in the presence of good disease control elsewhere in the body. 22986231 2012