Disease: Mental Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 GeneticVariation disease BEFREE Common SNPs in BICC1 and PCLO were associated with a 50% and 30% decreased risk of depression, respectively. 26391493 2016
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease BEFREE Here, we aimed to assess how recently associated PCLO and CACNA1C depression risk alleles jointly affect memory-related CG25 activity as an intermediate phenotype in clinically healthy humans. 24643163 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease BEFREE The association between PCLO and memory bias, as well as interaction between PCLO and childhood events was studied in patients remitted from depression (N = 299), as well as a sample of healthy individuals (N = 157). 25379724 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET The association between PCLO and memory bias, as well as interaction between PCLO and childhood events was studied in patients remitted from depression (N = 299), as well as a sample of healthy individuals (N = 157). 25379724 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET Here, we aimed to assess how recently associated PCLO and CACNA1C depression risk alleles jointly affect memory-related CG25 activity as an intermediate phenotype in clinically healthy humans. 24643163 2014
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET The piccolo (PCLO) gene, involved in monoaminergic neurotransmission, has previously been linked to depression in a genome-wide association study. 23620758 2013
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 GeneticVariation disease BEFREE The piccolo (PCLO) gene, involved in monoaminergic neurotransmission, has previously been linked to depression in a genome-wide association study. 23620758 2013
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET Monoaminergic modulation of the HPA system may be one possible pathomechanism by which PCLO exerts its effect on depression. 22832399 2011
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease BEFREE Monoaminergic modulation of the HPA system may be one possible pathomechanism by which PCLO exerts its effect on depression. 22832399 2011
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease BEFREE While monoamine signaling has preoccupied the bulk of scientific investigation to date, nontraditional gene candidates such as PCLO and GRM7 are now emerging and beginning to change the landscape for future human and animal research on depression. 20159343 2010
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 GeneticVariation disease BEFREE We aimed to validate the association of single-nucleotide polymorphism (SNP) rs2522833 in the PCLO gene with depression in the Rotterdam Study, a prospective population-based cohort of elderly persons. 19942622 2010
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET We aimed to validate the association of single-nucleotide polymorphism (SNP) rs2522833 in the PCLO gene with depression in the Rotterdam Study, a prospective population-based cohort of elderly persons. 19942622 2010