GNB3, G protein subunit beta 3, 2784

N. diseases: 192; N. variants: 10
Disease: Depressed mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.040 GeneticVariation phenotype BEFREE Study subjects with recessive alleles in 3 GNβ3 SNPs (Rs2301339, Rs5443, and Rs5446) had worse symptom severity (P = .011), worse mental health (P = .03), and higher depression scores (P = .005) despite no associations with GERD phenotypes or reflux metrics. 29148080 2018
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.040 GeneticVariation phenotype BEFREE The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression. 21709600 2011
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.040 GeneticVariation phenotype BEFREE The GNB3 C825T polymorphism and depression among subjects with alcohol dependence. 16897596 2007
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.040 GeneticVariation phenotype BEFREE In patients with functional dyspepsia, altered alpha-adrenoreceptor function and depression are prevalent, features that are linked to a G-protein beta 3 (GNB3) subunit gene polymorphism (C825T). 15057736 2004