GNRH1, gonadotropin releasing hormone 1, 2796

N. diseases: 179; N. variants: 2
Disease: Hypogonadism, Isolated Hypogonadotropic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3489396
Disease: Hypogonadism, Isolated Hypogonadotropic
Hypogonadism, Isolated Hypogonadotropic 		0.310 GeneticVariation disease BEFREE The discovery in 1977 of a hypogonadal mouse lacking GnRH (hpg mice) and, in 1986, that the gnrh1 gene was deleted in this mouse, suggested that GNRH1 mutations might also cause human congenital idiopathic (or isolated) hypogonadotropic hypogonadism.This was finally demonstrated in 2009. 20389089 2010
CUI: C3489396
Disease: Hypogonadism, Isolated Hypogonadotropic
Hypogonadism, Isolated Hypogonadotropic 		0.310 Therapeutic disease CTD_human [Testosterone and infertility]. 20063086 2010