GOT1, glutamic-oxaloacetic transaminase 1, 2805

N. diseases: 71; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 AlteredExpression disease BEFREE Analysis of enzymes that mediate the conversion of glutamate to AKG shows that TAZ/YAP induce glutamic-oxaloacetic transaminase (GOT1) and phosphoserine aminotransferase (PSAT1) expression and that TAZ/YAP activity positively correlates with transaminase expression in breast cancer patients. 29661856 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.020 AlteredExpression disease BEFREE High levels of GOT1 were further linked to poor survival as analysed by the GEPIA web tool, in thyroid and breast carcinoma and in lung adenocarcinoma. 29751795 2018