IFNL3, interferon lambda 3, 282617

N. diseases: 175; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 GeneticVariation disease BEFREE The patient had the IL-28B gene polymorphism rs12979860 CT genotype, which is associated not only with antiviral therapy response but also with diabetes risk after liver transplantation for hepatitis C. 25204264 2015
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 GeneticVariation disease BEFREE Prevalence of diabetes was significantly lower in patients with both favorable alleles (AA) than that with at least one unfavorable IL28B G allele (21.1 vs. 30.2 %, p = 0.02). 25663241 2015
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 GeneticVariation disease BEFREE The combination of PNPLA-3 non-CC and IL28B TT genotype was associated with increased risk of diabetes/IFG compared to PNPLA-3 CC, IL28B non-TT (HR 2.64, CI 1.30-5.39, p = 0.008). 23859071 2013