IFNL3, interferon lambda 3, 282617

N. diseases: 175; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019189
Disease: Hepatitis, Chronic
Hepatitis, Chronic
0.020 GeneticVariation disease BEFREE IL-28B rs12979860 polymorphism affect the course of chronic hepatitis and the development of HCC in Egyptian patients with hepatitis C type 4. 29914308 2018
CUI: C0019189
Disease: Hepatitis, Chronic
Hepatitis, Chronic
0.020 GeneticVariation disease BEFREE We analyzed 230 TM patients with HCV infection (mean age 36.0±6.3 years; 59.1% genotype 1; 32.2% genotype 2; 3.4% genotype 3; and 5.3% genotype 4; 28.7% carried CC allele of rs12979860 in IL28B locus; 79.6% had chronic hepatitis and 20.4% cirrhosis; 63.5% naive and 36.5% previously treated with interferon alone) treated in 14 Italian centers. 27012446 2016