IFNL3, interferon lambda 3, 282617

N. diseases: 175; N. variants: 8
Disease: Acute infectious disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease 		0.040 Biomarker group BEFREE Here, we examined the role played by interferon lambda-4 (IFN-λ4) on HCV diversity; IFN-λ4 plays a crucial role in spontaneous clearance or establishment of chronicity following acute infection. 31478835 2019
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease 		0.040 GeneticVariation group BEFREE In contrast, higher cytokine production of NK cells was observed in healthy individuals with the IFNL3-CC genotype, which may support spontaneous HCV clearance in acute infection. 26034208 2015
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease 		0.040 GeneticVariation group BEFREE The interleukin-28B (IL-28B) genotype is important in an HCV infection: it is related to the clinical severity of an acute infection and may play a role in the development of FCH as well. 24039107 2013
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease 		0.040 GeneticVariation group BEFREE Clinical data were available in 136 women with acute infection who were also evaluated for IL28B genotype. 20637200 2010