Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
GWASCAT |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
Inflammatory Bowel Diseases
|
0.400 |
GeneticVariation
|
group |
GWASDB |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
Inflammatory Bowel Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
|
21983784 |
2011 |
Crohn Disease
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
Gene-gene interaction analysis revealed significant interactions between MST1 and other susceptibility genes, including NOD2, MUC19 and ATG16L1 in contributing to Crohn's disease risk.
|
29441677 |
2018 |
Crohn Disease
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
In a CD GWAS-imputed using haplotype reference consortium data (64 976 haplotypes)-we could confirm the syntheses of MUC19 and PER3 and identified synthesis by missense variants for 6 further genes (ZGPAZ, GPR65, CLN3/NPIPB8, LOC102723878, rs2872507, GCKR).
|
27153721 |
2016 |
Crohn Disease
|
0.130 |
GeneticVariation
|
disease |
BEFREE |
Three MUC19 SNPs were nominally significantly associated with CD (rs11564245, Asp→His: P = 0.02; rs4768261, Ser→Phe: P = 0.0008; and rs2933353, Glu→Ala: P = 0.01).
|
23619718 |
2013 |
Crohn Disease
|
0.130 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
Crohn Disease
|
0.130 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
Idiopathic Pulmonary Fibrosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Secreted mucins (MUC2, MUC5AC, MUC5B, MUC6-8 and MUC19) are released to the extracellular medium and recent evidence has shown that a promoter polymorphism in the secreted mucin MUC5B is associated with IPF risk.
|
31514468 |
2019 |
Cerebellar Ataxia, Mental Retardation, And Dysequilibrium Syndrome 1
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to explore the expression of MUC5AC and MUC19 on the ocular surface in a DES model of ovariectomized female rabbits.
|
30640414 |
2019 |
Malignant neoplasm of breast
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our findings suggest an oncogenic role for hsa_circ_0007534 in BC by acting as a miR-593 sponge to promote MUC19 expression.
|
30139516 |
2018 |
Breast Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our findings suggest an oncogenic role for hsa_circ_0007534 in BC by acting as a miR-593 sponge to promote MUC19 expression.
|
30139516 |
2018 |
Ankylosing spondylitis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The current study evaluated whether three previously reported AS-associated single-nucleotide polymorphisms (SNPs), rs6908425 T>C in CDKAL1, rs11584383 T>C near KIF21B, and rs11175593 C>T near LRRK2/MUC19, have any genetic overlap across multiple autoimmune diseases including SAPHO syndrome, RA, AS, and SPA.
|
27936930 |
2017 |
Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Different Contributions of CDKAL1, KIF21B, and LRRK2/MUC19 Polymorphisms to SAPHO Syndrome, Rheumatoid Arthritis, Ankylosing Spondylitis, and Seronegative Spondyloarthropathy.
|
27936930 |
2017 |
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Association could be explained by missense variants for MUC19, PER3 (CD) and HMG20A (T2D).
|
27153721 |
2016 |
Dental caries
|
0.010 |
Biomarker
|
disease |
BEFREE |
Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva.
|
25512380 |
2015 |
Caries (morphologic abnormality)
|
0.010 |
Biomarker
|
disease |
BEFREE |
Salivary mucin 19 glycoproteins: innate immune functions in Streptococcus mutans-induced caries in mice and evidence for expression in human saliva.
|
25512380 |
2015 |
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
MEC was associated with MUC 19 expression in 65% of tumor samples compared to only 26% of normal tissue (P = .02).
|
21072847 |
2011 |
Mucoepidermoid Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MEC was associated with MUC 19 expression in 65% of tumor samples compared to only 26% of normal tissue (P = .02).
|
21072847 |
2011 |
Laryngitis
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.
|
18834073 |
2008 |
Sjogren's Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
MUC19 expression in human ocular surface and lacrimal gland and its alteration in Sjögren syndrome patients.
|
18184611 |
2008 |
Asthma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Five orthologous genes (MUC2, MUC5AC, MUC5B, MUC6, and MUC19) encode the mammalian gel-forming mucin family, and several have been implicated in asthma, cystic fibrosis, and chronic obstructive pulmonary disease pathologies.
|
17463395 |
2007 |