NUDT7, nudix hydrolase 7, 283927

N. diseases: 4; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.300 Biomarker group CTD_human Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. 25058030 2014
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.300 Biomarker disease CTD_human Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. 25058030 2014
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.010 Biomarker disease BEFREE Here we show a role for NUDT7 in OA pathogenesis. 30143643 2018
CUI: C2678439
Disease: CRANIOOSTEOARTHROPATHY
CRANIOOSTEOARTHROPATHY 		0.010 Biomarker disease BEFREE Two mammalian Nudix hydrolases, Nudt19 and Nudt7, degrade CoA <i>in vitro</i> Nudt19 and Nudt7 possess conserved Nudix and CoA signature sequences and specifically hydrolyze the diphosphate bond of free CoA and acyl-CoAs to form 3',5'-ADP and 4'-(acyl)phosphopantetheine. 29378847 2018