ANGPT1, angiopoietin 1, 284

N. diseases: 340; N. variants: 18
Disease: Diabetes Mellitus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE Restoring a more physiological Tie2-Ang1 axis with sildenafil reestablishes serum angiogenic properties in diabetes, promoting angiogenic homeostasis. 31102457 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE Co-administration of C21 and Dize augmented ACE2, Ang-(1-7), AT2R and MasR expressions, and attenuated tubular injury in both DM and ND rats. 31470003 2019
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE Diabetes prevented the mobilization of LSK cells in response to ischemia and impaired the recovery of blood flow, both of which were reversed by ANG-(1-7) in both models of diabetes. 27856608 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE This study investigated the effects of Ang-(1-7) on diabetes-induced cognitive deficits. 28147245 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE There is little data on the effects of angiopoietin-1 in adipose tissue and kidney in streptozotocin (STZ)-induced diabetes. 29212268 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 GeneticVariation group BEFREE Following 3 weeks of Ang-(1-7) treatment subsequent to induction of diabetes, rats were sacrificed. 28299329 2017
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE Diabetes-induced nephrin phosphorylation was also reduced in mice with angiopoietin-1 repletion. 24009238 2014
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.080 Biomarker group BEFREE Human umbilical cord blood cells is an effective neurorestorative therapy in T1DM-MCAo rats and the enhanced vascular and WM remodeling and associated functional recovery after stroke may be attributed to increasing Angiopoietin-1 and decreasing RAGE. 25042092 2014