ANGPT1, angiopoietin 1, 284

N. diseases: 340; N. variants: 18
Disease: Adult Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 Biomarker disease BEFREE Fibulin-7 is overexpressed in glioblastomas and modulates glioblastoma neovascularization through interaction with angiopoietin-1. 30924128 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 GeneticVariation disease BEFREE The Ang-(1-7) was proven to have an inhibitory effect on glioblastoma growth. 30229380 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 Biomarker disease BEFREE Using two patient-derived novel primary cell culture models (MTA10 and KW10), we developed a minimal but unique four-gene signature comprising genes vascular endothelial growth factor A (VEGF-A), vascular endothelial growth factor B (VEGF-B) and angiopoietin 1 (ANG1), angiopoietin 2 (ANG2) that effectively segregated the proneural (MTA10) and mesenchymal (KW10) glioblastoma subtypes. 28744448 2017
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 Biomarker disease BEFREE Differential regulation of VEGF, HIF1alpha and angiopoietin-1, -2 and -4 by hypoxia and ionizing radiation in human glioblastoma. 14712484 2004
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 Biomarker disease BEFREE Coculture of glioblastoma cell lines producing Ang1 with endothelium demonstrated a key role of this ligand in the control of EC network organization. 11304469 2001
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma 		0.060 AlteredExpression disease BEFREE Whereas Ang-1 mRNA was expressed in tumor cells, Ang-2 mRNA was detected in endothelial cells of a subset of glioblastoma blood vessels. 9811337 1998