|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
We found that the miR-181a-5p inhibitor significantly decreased the secretion of inflammatory factors, and the levels of creatine (Cr), blood urea nitrogen (BUN), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in a serum for mice with sepsis.
|
31844680 |
2019 |
|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
Aspartate and alanine transaminase elevations occurring before treatment discontinuation were grade 1, except 1 grade 3 event each, secondary to sepsis.
|
30803990 |
2019 |
|
Sepsis
|
0.290 |
GeneticVariation
|
disease |
BEFREE |
There were no significant differences in weight gain, nutrition indices, inflammation cytokine markers, and sepsis between the groups at the end of 2 and 4 weeks; however, in the SMOF group, the ALT, AST, and DB levels were significantly lower than the MCT/LCT group at the end of 4 weeks.
|
30474700 |
2019 |
|
Sepsis
|
0.290 |
AlteredExpression
|
disease |
BEFREE |
The results demonstrated that 2% H<sub>2</sub> gas inhalation resulted in an increase in the 7-day survival rate, ALT and AST levels, RCR, and P62 and LC3B-II expression but decreased the histological score and FUDNC1, P-18-FUDNC1, Tim23, and caspase-1 levels after sepsis.
|
30877875 |
2019 |
|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
This group also had lower peak aspartate aminotransferase (P = 0.07), alanine aminotransferase (P = 0.06) and lower rates of sepsis (P = 0.08) trending toward statistical significance.
|
29334530 |
2018 |
|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
In our study, we found that AA decreased levels of interleukin-1β (IL-1β), IL-6, alanine aminotransferase and blood urea nitrogen in serum; attenuated liver, lung and kidney damage; and improved the survival among mice with experimental sepsis.
|
29599924 |
2018 |
|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
HIPK2 expression was reduced in sepsis-induced liver injury, and HIPK2 overexpression increased the survival rate and improved caecal ligation and puncture (CLP)-induced liver injury by reducing serum and liver aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) levels in mice with sepsis.
|
30154452 |
2018 |
|
Sepsis
|
0.290 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, patients with sepsis had high levels of hepatocyte cfDNA, which correlated with levels of liver enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT).
|
29925683 |
2018 |
|
Sepsis
|
0.290 |
Biomarker
|
disease |
BEFREE |
To determine if elevated aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio is specific to histoplasmosis or a non-specific marker for disseminated fungal infection or sepsis in general, we retrospectively examined records of all patients diagnosed with an endemic fungal infection (EFI) at Rush University Medical Center from January of 1997 to October of 2012, and a cohort of septic patients with elevated liver enzymes.
|
27744308 |
2017 |
|
Sepsis
|
0.290 |
Therapeutic
|
disease |
RGD |
[Rosiglitazone protects against endotoxin-induced acute liver injury in rats].
|
26814114 |
2015 |