GPX2, glutathione peroxidase 2, 2877

N. diseases: 60; N. variants: 1
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 Biomarker phenotype BEFREE Herein, we identified the role of GPX2 in epithelial-mesenchymal transformation (EMT), invasion, and metastasis in PC. 31774184 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 AlteredExpression phenotype BEFREE We found that GPX2 was highly expressed in cervical cancer tissues compared to normal individuals and promoted the proliferation and metastasis of cervical cancer cells, and this promotion correlated with the activation of EMT and WNT/β-catenin signaling in vitro. 31695405 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 AlteredExpression phenotype BEFREE While there was no significant association between GPx2 expression and patient age, sex, T-stage, N-stage and the metastasis. 28453466 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 Biomarker phenotype BEFREE GPX2 protein underexpression was also significantly associated with advanced pT status, nodal metastasis, high histological grade, vascular invasion, and frequent mitoses in both groups of UCs (all p < 0.05). 25813210 2015
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 Biomarker phenotype CTD_human In conclusion, expression of GPX2 is associated with cancer metastasis from rat HCCs both in vitro and in vivo. 23867582 2013
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.350 AlteredExpression phenotype BEFREE In conclusion, expression of GPX2 is associated with cancer metastasis from rat HCCs both in vitro and in vivo. 23867582 2013