ANK3, ankyrin 3, 288

N. diseases: 106; N. variants: 58
Disease: Major Depressive Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 Biomarker disease BEFREE Three samples with major depressive disorder (total=671) were genotyped for 44 SNPs in 8 candidate genes (CACNA1C, CACNB2, ANK3, GRM7, TCF4, ITIH3, SYNE1, FKBP5). 28989100 2018
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 GeneticVariation disease GWASCAT Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. 23453885 2013
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 GeneticVariation disease BEFREE Several SNPs in both genes were nominally associated with MDD with the highest association in the 3'-region of ANK3 (rs10994143, nominal p = 3.3*10(-4)) in the metaanalysis of both samples. 22647524 2012
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 GeneticVariation disease GWASDB Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715 2011
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 GeneticVariation disease GWASCAT Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. 20351715 2011
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.130 GeneticVariation disease BEFREE The rs10994336 ANK3 and rs1006737 CACNA1C genetic variants have recently been identified as the most consistent, genome-wide significant risk factors for bipolar disorder, while the CACNA1C variant has also been associated with schizophrenia and major depression. 21676128 2011