GRB2, growth factor receptor bound protein 2, 2885

N. diseases: 122; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.010 Biomarker disease BEFREE These findings suggest that GRB2 plays an important role in CCl<sub>4</sub>-induced hepatic fibrosis by regulating HSCs' function, and up-regulation of GRB2 induced by HMGB1 is mediated via the PI3K/AKT pathway. 28618656 2017