GRN, granulin precursor, 2896

N. diseases: 412; N. variants: 66
Disease: Apathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085632
Disease: Apathy
Apathy 		0.120 GeneticVariation phenotype BEFREE In clear contrast with TBK1 carriers, GRN carriers were more often diagnosed with the language variant than the behavioural variant, and presented in case of the diagnosis of behavioural variant, more often than TBK1 carriers with apathy as the predominant characteristic (P = 0.004). 26674655 2016
CUI: C0085632
Disease: Apathy
Apathy 		0.120 GeneticVariation phenotype BEFREE The most common clinical presentation seen in GRN mutation carriers was behavioural variant FTLD with apathy as the dominant feature. 18234697 2008
CUI: C0085632
Disease: Apathy
Apathy 		0.120 Biomarker phenotype HPO