GRN, granulin precursor, 2896

N. diseases: 412; N. variants: 66
Disease: Plaque, Amyloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2936349
Disease: Plaque, Amyloid
Plaque, Amyloid 		0.010 AlteredExpression disease BEFREE This elevated PGRN expression significantly reduced amyloid plaque burden in these mice, accompanied by reductions in markers of inflammation and synaptic atrophy. 28837568 2017