|
Bipolar Disorder
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Only the BD brain demonstrated increased global histone H3 acetylation and hypermethylation of the promotor region for the drebrin-like protein gene.
|
22760556 |
2012 |
|
Bipolar Disorder
|
0.310 |
PosttranslationalModification
|
disease |
BEFREE |
Only the BD brain demonstrated increased global histone H3 acetylation and hypermethylation of the promotor region for the drebrin-like protein gene.
|
22760556 |
2012 |
|
Rhabdomyolysis
|
0.100 |
GeneticVariation
|
phenotype |
CLINVAR |
Exome sequencing in Jewish and Arab patients with rhabdomyolysis reveals single-gene etiology in 43% of cases.
|
28779239 |
2017 |
|
Glycogen storage disease type X
|
0.100 |
CausalMutation
|
disease |
CLINVAR |
Phosphoglycerate mutase deficiency (glycogen storage disease X) caused by a novel variant in PGAM-M.
|
27612597 |
2016 |
|
Glycogen storage disease type X
|
0.100 |
CausalMutation
|
disease |
CLINVAR |
The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency.
|
8447317 |
1993 |
|
Glycogen storage disease type X
|
0.100 |
GeneticVariation
|
disease |
CLINVAR |
|
|
|
|
Amyotrophic Lateral Sclerosis
|
0.020 |
Biomarker
|
disease |
BEFREE |
Furthermore, the mean F-wave amplitude (<i>r</i> = 0.454, <i>P</i> = 0.002) of the FDI was significantly correlated with the FDI/ADM CMAP amplitude ratio in ALS patients with affected hands but not of the ADM. Our findings suggested that the dysfunction of spinal motoneurons between the FDI and ADM was different in ALS, and spinal motoneuron dysfunction was associated with development of the split-hand phenomenon.
|
31133773 |
2019 |
|
Amyotrophic Lateral Sclerosis
|
0.020 |
Biomarker
|
disease |
BEFREE |
In older subjects, the CMAP amplitude decreased with age, but the decrement was increased only in ADM. At the baseline study the CMAP amplitude was similar in all three muscles in control and ALS patients.
|
31056952 |
2019 |
|
Neoplasm Metastasis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
MBNL1 binds the 3' untranslated regions (UTRs) of DBNL (drebrin-like protein) and TACC1 (transforming acidic coiled-coil containing protein 1)-two genes that we implicate as metastasis suppressors.
|
26883358 |
2016 |
|
Neoplasm Metastasis
|
0.020 |
AlteredExpression
|
phenotype |
BEFREE |
CMAP mRNA was selectively overexpressed in all murine liver metastatic tumors but not in any pulmonary metastatic tumors examined.
|
9892200 |
1999 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
Biomarker
|
disease |
BEFREE |
CMAP: compound muscle action potential; cSNCV: compound sensory nerve conduction velocity; IENFD: intraepidermal nerve fiber density; LDL: low-density lipoprotein; MetS: metabolic syndrome; MNCV: motor conduction velocity; NCV: nerve conduction velocity; PN: peripheral neuropathy; PNS: peripheral nervous system; STZ: streptozotocin; T2D: type 2 diabetes mellitus; TNF alpha: tumor necrosis factor alpha; WHO: World Health Organization.
|
30638160 |
2019 |
|
Peripheral Neuropathy
|
0.010 |
Biomarker
|
group |
BEFREE |
CMAP: compound muscle action potential; cSNCV: compound sensory nerve conduction velocity; IENFD: intraepidermal nerve fiber density; LDL: low-density lipoprotein; MetS: metabolic syndrome; MNCV: motor conduction velocity; NCV: nerve conduction velocity; PN: peripheral neuropathy; PNS: peripheral nervous system; STZ: streptozotocin; T2D: type 2 diabetes mellitus; TNF alpha: tumor necrosis factor alpha; WHO: World Health Organization.
|
30638160 |
2019 |
|
Lissencephaly
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results suggest that Dbnl controls neuronal migration, neuronal multipolar morphology, and cell polarity in the developing cerebral cortex via regulating N-cadherin expression.<b>SIGNIFICANCE STATEMENT</b> Disruption of neuronal migration can cause neuronal disorders, such as lissencephaly and subcortical band heterotopia.
|
30504273 |
2019 |
|
Metabolic Syndrome X
|
0.010 |
Biomarker
|
disease |
BEFREE |
CMAP: compound muscle action potential; cSNCV: compound sensory nerve conduction velocity; IENFD: intraepidermal nerve fiber density; LDL: low-density lipoprotein; MetS: metabolic syndrome; MNCV: motor conduction velocity; NCV: nerve conduction velocity; PN: peripheral neuropathy; PNS: peripheral nervous system; STZ: streptozotocin; T2D: type 2 diabetes mellitus; TNF alpha: tumor necrosis factor alpha; WHO: World Health Organization.
|
30638160 |
2019 |
|
Subcortical Band Heterotopia
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results suggest that Dbnl controls neuronal migration, neuronal multipolar morphology, and cell polarity in the developing cerebral cortex via regulating N-cadherin expression.<b>SIGNIFICANCE STATEMENT</b> Disruption of neuronal migration can cause neuronal disorders, such as lissencephaly and subcortical band heterotopia.
|
30504273 |
2019 |
|
Length-dependent peripheral neuropathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study demonstrates the high correlation between the tibial CMAP and the sural SNAP in subjects without PN and patients with mild axonal peripheral neuropathy, and provides mathematical equations for the calculation of the predicted tibial CMAP for such individuals.
|
31686383 |
2019 |
|
Peripheral Nervous System Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
CMAP: compound muscle action potential; cSNCV: compound sensory nerve conduction velocity; IENFD: intraepidermal nerve fiber density; LDL: low-density lipoprotein; MetS: metabolic syndrome; MNCV: motor conduction velocity; NCV: nerve conduction velocity; PN: peripheral neuropathy; PNS: peripheral nervous system; STZ: streptozotocin; T2D: type 2 diabetes mellitus; TNF alpha: tumor necrosis factor alpha; WHO: World Health Organization.
|
30638160 |
2019 |
|
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
R1 prolongation correlated with more severely affected NCS in both POEMS (ulnar CMAP 2.6 mV vs. 4.5 mV, P = 0.001) and CIDP (2.0 mV vs. 6.1 mV, P < 0.001).
|
28646568 |
2018 |
|
CATARACT, MARNER TYPE
|
0.010 |
Biomarker
|
disease |
BEFREE |
Cobl-like-mediated dendritic branching is dependent on Abp1 as well as on Ca<sup>2+</sup>/calmodulin (CaM) signaling and CaM association.
|
29233863 |
2018 |
|
Cavernous Hemangioma of Brain
|
0.010 |
Biomarker
|
disease |
BEFREE |
Cobl-like-mediated dendritic branching is dependent on Abp1 as well as on Ca<sup>2+</sup>/calmodulin (CaM) signaling and CaM association.
|
29233863 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Enrichment analysis of the signature with curated cancer genes and the drugs selected by CMAP showed the genes in the signature may be drug targets for therapy.
|
28615526 |
2017 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Enrichment analysis of the signature with curated cancer genes and the drugs selected by CMAP showed the genes in the signature may be drug targets for therapy.
|
28615526 |
2017 |
|
Diabetes Mellitus
|
0.010 |
Biomarker
|
group |
BEFREE |
Amplitudes of ulnar CMAP are lower in patients with CMT1A and diabetes mellitus, but not at a significant level.
|
23891256 |
2013 |
|
Muscular Atrophy, Spinal, Type II
|
0.010 |
Biomarker
|
disease |
BEFREE |
Tibial nerve CMAP amplitudes significantly reduced in SMA II patients (p<0.01).
|
22512990 |
2013 |
|
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Analysis of the K-ras/B-raf/Erk signal cascade, p53 and CMAP as markers for tumor progression in colorectal cancer patients.
|
18575712 |
2008 |