Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 Biomarker disease BEFREE A natural product from Cannabis sativa subsp. sativa inhibits homeodomain-interacting protein kinase 2 (HIPK2), attenuating MPP<sup>+</sup>-induced apoptosis in human neuroblastoma SH-SY5Y cells. 28366826 2017
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 Biomarker disease BEFREE Here we report that Galectin-3 impairs MYCN-primed and HIPK2-p53-dependent apoptosis in neuroblastoma cells. 23152863 2012
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.030 AlteredExpression disease BEFREE Prompted by the rare occurrence of p53 mutations and by the broad expression of HIPK2 in our human neuroblastoma series, we evaluated the effects of the p53-reactivating compound Nutlin-3 on this pathway. 21173028 2011