KLF15, Kruppel like factor 15, 28999

N. diseases: 80; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.030 Biomarker disease BEFREE Loss of KLF4 and KLF15 promotes renal fibrosis, while fibrotic kidneys have increased KLF5 and KLF6 expression. 30662001 2019
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.030 AlteredExpression disease BEFREE Compared with the control group, the murine model of Ang II-induced renal fibrosis demonstrated a significant decrease in renal KLF15 expression at 4 weeks and presented with progressive renal fibrosis at 6 weeks. 29179208 2017
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.030 AlteredExpression disease BEFREE Here, we tested whether Klf15 mRNA and protein expression are reduced in late stages of fibrosis in mice that underwent unilateral ureteric obstruction, a model of progressive renal fibrosis. 28651950 2017