ANPEP, alanyl aminopeptidase, membrane, 290

N. diseases: 280; N. variants: 4
Disease: Epidemic diarrhea ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 Biomarker disease BEFREE Collectively, this report provides a viable tool for producing animals with enhanced resistance to TGEV and clarifies that APN is dispensable for the PEDV infection in pigs. 31515498 2019
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 AlteredExpression disease BEFREE Hence, the reduction in APN expression represents another component of the anti-PEDV infection response initiated by ADAM17. 29475600 2018
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 Biomarker disease BEFREE The combined observations indicated that APN is not required for PEDV infection. 28363778 2017
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 Biomarker disease BEFREE Although PEDV was long believed to replicate in the intestinal epithelium by using aminopeptidase N as a receptor, the mechanisms of PEDV infection are not fully characterized. 28275187 2017
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 Biomarker disease BEFREE Furthermore, we revealed that aminopeptidase N was involved in PEDV infection in HEK293 cells. 28470417 2017
CUI: C0277527
Disease: Epidemic diarrhea
Epidemic diarrhea 		0.060 Biomarker disease BEFREE Taken together, our results suggest that pAPN receptor density appears to be an important factor in contributing to efficient PEDV infection. 20074871 2010