SCG3, secretogranin III, 29106

N. diseases: 24; N. variants: 5
Disease: Retinopathy of Prematurity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.020 Biomarker disease BEFREE Secretogranin III (Scg3) was recently discovered as a highly disease-restricted angiogenic factor, and a Scg3-neutralizing monoclonal antibody (mAb) was reported with high efficacy to alleviate oxygen-induced retinopathy (OIR) in mice, a surrogate model of ROP. 30644010 2019
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.020 Biomarker disease BEFREE Furthermore, anti-Scg3 prevented retinal neovascularization in oxygen-induced retinopathy mice, a surrogate model for retinopathy of prematurity (ROP). 28330905 2017