GRM4, glutamate metabotropic receptor 4, 2914

N. diseases: 54; N. variants: 5
Disease: Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 AlteredExpression disease BEFREE Analysis of TCGA database showed that there was no substantial deviation in the expression of GRM4 between osteosarcoma and normal tissues. 31581881 2020
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 Biomarker disease BEFREE Agonists of GRM4 or a neutralizing antibody to IL23 suppressed osteosarcoma growth in mice. 31527131 2019
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 GeneticVariation disease BEFREE The aim of this study was to investigate the association between polymorphism of the GRM4 gene and the susceptibility to osteosarcoma in a Chinese population. 26276359 2016
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 AlteredExpression disease BEFREE The results of Western blot and RT-PCR indicated a significantly increased expression level of mGluR4 gene and protein in osteosarcoma tissues compared with normal tissues. 24399291 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 GeneticVariation disease BEFREE The GRM4 gene polymorphism was associated with the susceptibility and metastasis of OS in a Chinese Han population. 24984297 2014
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 GeneticVariation disease GWASDB Genome-wide association study identifies two susceptibility loci for osteosarcoma. 23727862 2013
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 GeneticVariation disease GWASCAT Genome-wide association study identifies two susceptibility loci for osteosarcoma. 23727862 2013
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.450 Biomarker disease CTD_human Genome-wide association study identifies two susceptibility loci for osteosarcoma. 23727862 2013