GRM5, glutamate metabotropic receptor 5, 2915

N. diseases: 189; N. variants: 37
Disease: Cocaine Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.320 Biomarker disease BEFREE This work further identifies glutamate homeostasis and mGlu5 as a target for treating relapse in comorbid PTSD-cocaine addiction. 30291225 2018
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.320 Biomarker disease BEFREE Glutamatergic Biomarkers for Cocaine Addiction: A Longitudinal Study Using MR Spectroscopy and mGluR5 PET in Self-Administering Rats. 29496988 2018
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.320 Biomarker disease CTD_human Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. 20826661 2010