CXCL1, C-X-C motif chemokine ligand 1, 2919

N. diseases: 315; N. variants: 3
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.060 AlteredExpression phenotype BEFREE 4-Methylbenzenecarbothioamide, a hydrogen sulfide donor, inhibits tumor necrosis factor-α and CXCL1 production and exhibits activity in models of pain and inflammation. 31132352 2019
CUI: C0030193
Disease: Pain
Pain 		0.060 Biomarker phenotype BEFREE The effects of NFκB and CXCR2 antagonists and CXCL1 neutralizing antibody on pain hypersensitivity were evaluated by behavioral testing. 30606213 2019
CUI: C0030193
Disease: Pain
Pain 		0.060 Biomarker phenotype BEFREE In this study, we investigated whether and how CXCL1 contributes to vincristine-induced pain and the underlying mechanisms of levo-corydalmine (l-CDL, a tetrahydroprotoberberine). 29518397 2018
CUI: C0030193
Disease: Pain
Pain 		0.060 Biomarker phenotype BEFREE CXCL1 is a chemokine with pleiotropic effects, including pain and itch. 28966134 2018
CUI: C0030193
Disease: Pain
Pain 		0.060 Biomarker phenotype BEFREE CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization. 28587921 2017
CUI: C0030193
Disease: Pain
Pain 		0.060 Biomarker phenotype BEFREE These data contribute to a better understanding of CXCL1 and CXCL2 mechanism of action for both pain and itch inducing effects. 28820395 2017