CXCL1, C-X-C motif chemokine ligand 1, 2919

N. diseases: 315; N. variants: 3
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE Macrophages are the major sources of CXCL1 and CXCL5 in the gastric cancer microenvironment, and promote migration of gastric cancer cells through activating a CXCR2/STAT3 feed-forward loop. 30796034 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE Further analysis showed high expression of CXCL8, COL3A1, CXCL1, MMP3 and SERPINE1, were significantly associated with late stage of GC. 31638362 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE Among the CXCR2 ligands, CXCL7 and especially CXCL1, might play an important role in the malignant progression of GC via CXCR2 signaling. 31810929 2019
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE Therefore, CXCL1 produced in T-LECs represents a potentially promising target for treating gastric cancer. 27832972 2017
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE CXCL1 gene silencing inhibits HGC803 cell migration and invasion and acts as an independent prognostic factor for poor survival in gastric cancer. 27748927 2016
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.060 Biomarker disease BEFREE These results provide strong evidence that CXCL1 plays an important role in gastric cancer progression and migration and suggest that CXCL1 is a promising marker for the detection and prognosis of gastric cancer. 21343381 2011