GRPR, gastrin releasing peptide receptor, 2925

N. diseases: 85; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 Biomarker disease BEFREE Radiolabeled bombesin (BBN)-analogs have been proposed for diagnosis and therapy of gastrin-releasing peptide receptor (GRPR)-expressing tumors, such as prostate, breast and lung cancer. 28636973 2017
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 AlteredExpression disease BEFREE Gastrin-releasing peptide receptor (GRPR) is differentially expressed on the surfaces of various diseased cells, including prostate and lung cancer. 26577829 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 GeneticVariation disease BEFREE The presence of two expressed copies of the GRPR gene in females may be a factor in the increased susceptibility of women to tobacco-induced lung cancer. 10620630 2000
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
0.040 AlteredExpression disease BEFREE Both GRP-R and NMB-R mRNA expression was detected at varying levels in a panel of human lung cancer cell lines. 1655761 1991